Sunday, March 15, 2020
Just an observation
As I sit here sipping my coffee, scrolling through the blogs and the social media on the inter-webs I can’t help but notice, at least all the Sites and comments I’ve read, that there isn’t any first-hand comments or posts of people experiencing the wuhan flu. They must be out there?
We have well over 50 people at my company and they have spouses and girlfriends and kids and friends and interact with countless other people and no one has anybody that knows anybody firsthand. I’ve asked my friends if any of them know anybody at work or know people they socialize with and their contacts with people on social media. Nada,nothing. I would have to imagine that myself being locked up for two weeks in my house that I would blogging about it to you guys until I couldn’t.
Granted we get about 14,000 hits a day and and, most likely, about 13,990 are bots that stopped by for the Feral Irishman Friday femme fatale post. That being said the 10 of you that do stop by here are all around the country and some around the globe. Only one person has mentioned to me that a possible family member might have it. Like I said it’s just an observation.
It’s a new day, the sun rose, the birds are chirping, cars are driving by on the street outside. Maybe this will all change as the clock ticks by.
Stay safe out there
Irish
Saturday, March 14, 2020
Above My Pay Grade...Genomic epidemiology of novel coronavirus (hCoV-19)
The links below were posted in this comment by Iska on this thread at THEBURNINGPLATFORM <<
I stumbled across this layman’s Twitter feed and now I’m checking in several times a day. https://twitter.com/__philipn__
As he says – “not a doctor or medical professional”, BUT he seems
smart and via this feed has been collecting and disseminating theories
and studies about possible use of ACE inhibitors and “ARBs” (Angiotensin
II Receptor Blockers) against COVID19. The initial theory was that
since the virus attacks via the ACE2 receptor, an ARB like Losartan
might block that receptor and deny the virus access to the cell. Not
sure that will prove to be true, but ARBs and ACEi’s seem to generally
stymie viruses.
A few days ago The Lancet published an article that theorizes that ARBs and ACEi’s might put people at greater risk – since they “upregulate” (increase) ACE2 (which the virus uses to attack), but the counter theory is that having high levels of ACE2 is necessary to avoid sever lung and heart damage. This theory goes on that the virus -after using ACE2 to gain entry – “downregulates” (decreases) ACE2, leaving the patient at grave risk of serious heart and lung damage. Therefore, ACEi’s and ARBs (both of which upregulate ACE2) are likely PROTECTIVE – the exact OPPOSITE of what the Lancet article says.
There are plenty of rabbit holes at that Twitter account to go down if you’re so-inclined. Here’s a good start: https://twitter.com/EricTopol/status/1238833421926858752
Hope Karl Denninger sees this. I got the Ban Hammer there long ago (LOL), but he should know that the Lancet article against hypertension meds is NOT universally accepted, by any means, and could have it EXACTLY backwards.
A few days ago The Lancet published an article that theorizes that ARBs and ACEi’s might put people at greater risk – since they “upregulate” (increase) ACE2 (which the virus uses to attack), but the counter theory is that having high levels of ACE2 is necessary to avoid sever lung and heart damage. This theory goes on that the virus -after using ACE2 to gain entry – “downregulates” (decreases) ACE2, leaving the patient at grave risk of serious heart and lung damage. Therefore, ACEi’s and ARBs (both of which upregulate ACE2) are likely PROTECTIVE – the exact OPPOSITE of what the Lancet article says.
There are plenty of rabbit holes at that Twitter account to go down if you’re so-inclined. Here’s a good start: https://twitter.com/EricTopol/status/1238833421926858752
Hope Karl Denninger sees this. I got the Ban Hammer there long ago (LOL), but he should know that the Lancet article against hypertension meds is NOT universally accepted, by any means, and could have it EXACTLY backwards.
One of the retweets from Eric Topol (link above) references this map and NEXTSTRAIN
Nextstrain is an open-source project to harness the scientific and public health potential of pathogen genome data.
Here is a map showing 497 of 497 genomes sampled between Dec 2019 and Mar 2020.
Link to the map LINK<<<
Below is the twitter post embedded
Thanks to #opendata sharing by @UW @UWVirology & @GISAID, we've updated https://t.co/SDPCOcsnMX to include 7 new sequences from Washington State.— Nextstrain (@nextstrain) March 14, 2020
Most cluster w prev WA samples, but 2 do not. From the nearby seqs, these may indicate infection while travelling to Iran & Europe. pic.twitter.com/UKVtpuA2b8
There are definitely lots of rabbit holes to follow.............
This Sums Up The Biden Campaign..
Speaking of Biden, meet Jason Howerton
The union worker who Joe Biden tried to intimidate and told he didn't need an "AR-14" literally got a rifle engraved with "AR-14" and "Full of shit."— Jason Howerton (@jason_howerton) March 14, 2020
This man is a gosh damn LEGEND. 🔥🇺🇸pic.twitter.com/F1GDgtXRmJ
Eff The Wuhan Flu... Wait Until Some Asshole Eats One Of These...
Bat Cat Soup? What Could Possibly Go Wrong?
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